An evaluation of the impact of a single-dose intravenous immunoglobulin regimen in the treatment of clostridium difficile infections

M.A. Aldeyab, J.C. McElnay, M.G. Scott, C. Edwards, Elizabeth Davies, F.W. Darwish Elhajji, G. Conlon, F.A. Magee, P.J. Barr, M.P. Kearney

Research output: Contribution to journalLetterpeer-review

7 Citations (Scopus)
Original languageEnglish
Pages (from-to)631-633
Number of pages3
JournalInfection Control and Hospital Epidemiology
Volume32
Issue number6
DOIs
Publication statusPublished - Jun 2011

Bibliographical note

Cited By :7

Export Date: 15 September 2018

CODEN: ICEPE

Correspondence Address: Aldeyab, M. A.; Clinical and Practice Research Group, School of Pharmacy, Queen's University Belfast, BT9 7BL Belfast, Northern Ireland, United Kingdom; email: m.aldeyab@qub.ac.uk

Chemicals/CAS: immunoglobulin, 9007-83-4; metronidazole, 39322-38-8, 443-48-1; vancomycin, 1404-90-6, 1404-93-9; Bacterial Toxins; Enterotoxins; Immunoglobulins, Intravenous; Immunologic Factors; tcdA protein, Clostridium difficile

References: Thompson, I., Clostridium difficile-associated disease: Update and focus on non-antibiotic strategies (2008) Age Ageing, 37, pp. 14-18; McFarland, L.V., Update on the changing epidemiology of Clostridium difficile-associated disease (2008) Nat Clin Pract Gastroenterol Hepatol, 5, pp. 40-48; Kyne, L., Warny, M., Qamar, A., Kelly, C.P., Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A (2000) N Engl J Med, 342, pp. 390-397; Leffler, D.A., Lamont, J.T., Treatment of Clostridium difficile-associated disease (2009) Gastroenterology, 136, pp. 1899-1912; Gerding, D.N., Muto, C.A., Owens, R.C., Treatment of Clostridium difficile infection (2008) Clin Infect Dis, 46 (1), pp. S32-S42; Halsey, J., Current and future treatment modalities for Clostridium difficile-associated disease (2008) Am J Health Syst Pharm, 65, pp. 705-715; O'Horo, J., Safdar, N., The role of immunoglobulin for the treatment of Clostridium difficile infection: A systematic review (2009) Int J Infect Dis, 13, pp. 663-667; Aldeyab, M.A., Devine, M.J., Flanagan, P., Multi-hospital outbreak of Clostridium difficile ribotype 027 infection: Epidemiology and analysis of control measures (2011) Infect Control Hosp Epidemiol, 32 (3), pp. 210-219; Tobacman, J.K., Assessment of comorbidity: A review (1994) Clin Perform Qual Health Care, 2, pp. 23-32

Keywords

  • immunoglobulin
  • metronidazole
  • vancomycin
  • aged
  • clinical article
  • Clostridium difficile infection
  • controlled study
  • human
  • length of stay
  • letter
  • male
  • single drug dose
  • treatment outcome
  • Aged, 80 and over
  • Bacterial Toxins
  • Clostridium difficile
  • Clostridium Infections
  • Enterotoxins
  • Female
  • Humans
  • Immunoglobulins, Intravenous
  • Immunologic Factors
  • Length of Stay
  • Male
  • Retrospective Studies
  • Treatment Outcome

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