Function of a long-term, GLP-1-treated, insulin-secreting cell line is improved by preventing DPP IV-mediated degradation of GLP-1

Keyphrases

• Glucagon-like 100%
• Dipeptidyl peptidase-IV (DPP-IV) 100%
• Insulin-producing Cells 100%
• Insulin 17%
• N-acetylation 17%
• Secretory Activity 11%
• Amides 11%
• Ongoing Development 5%
• Insulin Secretion 5%
• Cell Growth 5%
• Beneficial Effects 5%
• Cell Behavior 5%
• Prolonged Exposure 5%
• Pancreatic β-cells 5%
• Type 2 Diabetes Prevention 5%
• Insulinotropic Effects 5%
• A1 Receptor 5%
• Insulin Content 5%
• Glucose Responsiveness 5%
• Biological Half-life 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Insulin 100%
• Glucagon-Like Peptide-1 100%
• Acetic Acid Derivative 18%
• Amide 12%
• Diprotin A 12%
• Peptide 6%
• Glucose 6%
• Hormone 6%
• Non Insulin Dependent Diabetes Mellitus 6%
• Long Term Exposure 6%
• Dipeptidyl Peptidase IV Inhibitor 6%
• Biological Half-Life 6%
• Glucagon-Like Peptide 1 Receptor 6%
• Desensitization 6%