Stem cell therapy has been envisaged for treating disorders affecting skeletal muscle tissue. The first myogenic stem cell which was proposed and used in clinical trials was the physiological muscle progenitor, i.e. the satellite cell.However, before considering intervention in skeletal muscle, one needs to know well the process of muscle regeneration, as well as the different pathologies that can be eligible for cell therapy. Here, we present an overview of muscle regeneration, the role of satellite cells, how the process is orchestrated,and a short overview on some muscular dystrophies.
|Title of host publication||Stem Cell Biology and Regenerative Medicine|
|Publication status||Published - 15 Oct 2014|
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- muscle stem cells and regeneration