The experience of fatigue for people living with hepatitis C

Michèle Glacken, Vivien Coates, George Kernohan, John Hegarty

Research output: Contribution to journalArticlepeer-review

52 Citations (Scopus)


• Hepatitis C affects approximately 3% of the world population, with fatiguebeing acknowledged as the cardinal symptom. Despite growing recognition thathepatitis C fatigue impacts in a negative manner on quality of life, at the time ofthis study no empirical information existed regarding the nature of this fatigue orthe way in which it affects a person’s life. Such information is needed to enablenurses to engage in appropriate sensitive symptom management which is the corenursing activity with this population, as to date there is no vaccine or widelyeffective pharmacological therapy.• The aim of the study was to ascertain the nature of hepatitis C fatigue.• A qualitative approach using a grounded theory approach was employed.Theoretical sampling generated 28 participants for in-depth interview. Dataanalysis consisted of three coding processes, each type of coding having its ownpurpose and method. Ethical approval was obtained, both from the principalauthor’s academic institution and the participating health care institution.• Hepatitis C fatigue emerged as being multidimensional in nature, with bothacute and chronic versions existing.• The hepatology community is beginning to acknowledge the significantprevalence of hepatitis C fatigue. This study provides a valuable insight into itsnature. This information can serve as resource for practitioners in theirdevelopment of interventions to enable the hepatitis C virus population live withfatigue in a proactive manner.
Original languageEnglish
Pages (from-to)244-252
JournalJournal of Clinical Nursing
Issue number2
Publication statusPublished - 2003


  • fatigue
  • grounded theory
  • hepatitis C virus


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